Capping And Lamination Of Tablets

Tablet capping and lamination powder compaction is widely used to produce pharmaceutical tablets and is referred to as a tabletting process. Lamination is separation that occurs at any other part of the tablet except the top or bottom. Lamination is also caused by the presence of a large amount of fines in the granulations.

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Although the method is widely used there are still significant challenges with achieving a high quality compact.

Capping and lamination of tablets.

Ejection issues could lead to lamination. As the air is released when the upper punch die tip is raised capping only occurs at the top of the tablet. If a fracture occurs in the lower part of the tablet it is referred to as lamination and is discussed below. Compressing the tablet too thin the only common factor between capping and lamination usually occurs at precompression causing the tablets to compress in layers and the layers will separate as tablets cool or the bottom layer will separate from top during ejection.

Capping happens when the upper or lower part of a tablet separates horizontally photo as the press ejects the tablet. The term tablet capping is used when either the upper or lower part of the tablet separates horizontally either partially away from the main body or completely to form a cap when ejected from the press or during the handling process. This challenge can be overcome by doing a pre compression as well as reducing the compression and minimizing the tableting rate. Capping and lamination are common defects that occur during tablet manufacturing.

First lamination is caused by air being trapped in the tablet especially among the granules or particles.

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